AI News, Artificial intelligence platform screens for acute neurological illnesses

Artificial intelligence platform screens for acute neurological illnesses

'With a total processing and interpretation time of 1.2 seconds, such a triage system can alert physicians to a critical finding that may otherwise remain in a queue for minutes to hours,' says senior author Eric Oermann, MD, Instructor in the Department of Neurosurgery at the Icahn School of Medicine at Mount Sinai.

'The expression 'time is brain' signifies that rapid response is critical in the treatment of acute neurological illnesses, so any tools that decrease time to diagnosis may lead to improved patient outcomes,' says study co-author Joshua Bederson, MD, Professor and System Chair for the Department of Neurosurgery at Mount Sinai Health System and Clinical Director of the Neurosurgery Simulation Core.

This study was performed by the Mount Sinai AI Consortium, known as 'AISINAI' -- a group of scientists, physicians, and researchers dedicated to developing artificial intelligence in medicine that will improve patient care and help doctors accurately diagnose disease.

Research Studies

The Leadership Sinai Centre for Diabetes regularly conducts clinical trials, and we invite participants to join our studies.

This effect on beta cells has allowed people with type 2 diabetes to then temporarily maintain blood sugar levels for several months afterwards without any diabetes medication.

At Mount Sinai Hospital, we are currently conducting clinical trial that focus on trying to maintain this remission, thus potentially modifying the natural history of type 2 diabetes.

The standard treatment for women with type 1 diabetes who are pregnant or planning pregnancy is the balancing of insulin, food and activity.

Continuous glucose monitoring systems measure the glucose levels in patients every five minutes and provide a graph of the trends of the blood sugars to help patients manage their diabetes.

We believe that adding metformin may help with blood sugar control, lower the dose of insulin needed, lower weight gain, and improve baby outcomes.

Although most women do not have any side effects, some side effects may include gastrointestinal discomfort, diarrhea, decreased appetite, and rarely metallic taste.

In this study, the levels of certain proteins or markers in the blood related to diabetes are being studied in both women with diabetes during pregnancy (gestational diabetes) and those without diabetes during pregnancy.

In the PERL study we are using a medication called allopurinol to see whether it may help prevent the loss of kidney function that sometimes occurs in people with Type 1 diabetes.

Allopurinol has been used for many years to decrease high blood uric acid and treat gout - a disease characterized by arthritis, especially of the foot joints.

There is some evidence suggesting that allopurinol might also be useful in people with diabetes who have normal kidney function or early to moderate kidney function loss by decreasing uric acid, therefore reducing the risk of developing kidney disease in the future.

To prove this beneficial effect of allopurinol, we are conducting an international clinical trial, together with other diabetes centers, enrolling approximately 480 patients in total.

The study involves 17 visits at our clinic, spread over about a 3 and ½ year period and taking four allopurinol or placebo capsules (inactive capsules that look like allopurinol), once a day during this time frame.

Ear, Nose and Throat (Otolaryngology)-Head and Neck Research Studies

Researchers at the Department of ENT (Otolaryngology)-Head and Neck Surgery andHead and Neck Cancer Research Programremain true to Mount Sinai’s mission to provide unrivaled patient care, education, and research to the various diverse communities we serve.

Our research efforts utilize a multidisciplinary approach in conducting clinical trials and studies that includetransoral robotic surgery (TORS), immune-based therapies, HPV-related head and neck cancers, and molecular pathways of tumor dormancy, growth, recurrence and metastasis.

Surgeons are studying patients with HPV-positive stage II-IV squamous cell carcinoma of the oropharynx who were treated with chemotherapy or radiation to offer new treatment options like the Advaxis vaccine.

Oral Cancer and Transoral Robotic Surgery (TORS)Researchers are studying the use of a 3D flexible tube with a light and camera during transoral robotic surgeries with the goal of better managing treatment for oropharyngeal squamous cell carcinomas.

Current clinical and experimental research is being conducted to explain the development and maintenance of tumor dormancy, including anti-angiogenesis, tumor immune surveillance, and tissue homeostasis.

OurCenter for Hearing and Balance teamis studying ways to effectively treat chronic ear disease and treatment results after surgery to identify factors that influence surgical outcomes.

Clinical Research Trials at the Sinai Cancer Care Center

PDF of current clinical trials Mount Sinai Hospital is proud to offer state-of-the-art cancer treatment through our oncology clinical trials program.

Our trained clinical research staff consistently set us apart with a comprehensive list of active clinical trials over a broad therapeutic area.

clinical trial is a research study to answer specific questions about vaccines or new therapies or new ways of using known treatments.

Clinical trials (also called medical research and research studies) are used to determine whether new drugs or treatments are both safe and effective. Carefully conducted clinical trials are the fastest and safest way to find treatments that work.

Every clinical trial in the U.S. must be approved and monitored by an Institutional Review Board (IRB) to make sure the risks are as low as possible and are worth any potential benefits.

Research Subject Recruitment

Recruiting participants is a crucial component of research studies involving human subjects.

In addition, while identifying a sufficient number of eligible participants, the research team must ensure that their recruitment methods and materials comply with all required regulatory standards.

All forms of advertising or dissemination of information for the purposes of recruitment of subjects into research studies must be approved by the Program for the Protection of Human Subjects (PPHS) Institutional Review Board (IRB)prior to the distribution or publication of the material.

The EpicCare EHR (Electronic Health Record) by the Mount Sinai Health System makes it possible for clinicians and clinical researchers to work together to offer the best options for patients, while helping alleviate the problem of recruitment shortfalls for clinical research studies.

Piloted by the Epic research team in the Clinical Trials Office of Tisch Cancer Institute, Epic Clinical Trial Alerts (CTAs) can help make a meaningful match between clinical researchers and clinicians who have recently seen potentially eligible candidates for their studies.

Epic CTAs appear in the Epic Electronic Health Record (EHR), visible to care providers at the point of care, indicating patients matching screening criteria for a clinical trial.

The following Local Census Statistics for East Harlem and the Upper East Side can provide researchers with the basis for feasibility studies and for describing the populations you plan to enroll for your grant proposals: QuickFacts provides the data from the US Census Bureau, the New York City Department of Health and Mental Hygiene 2006, 2009, and by City-Data.

MSDW provides access to clinical and financial data derived from patient care processes of The Mount Sinai Hospital and Faculty Practice Associates since 2003, encompassing over 3 million patients (inpatient, outpatient, and emergency visits), approaching one billion facts.

The Mount Sinai Health System Patient Population Statistics 2016provides researchers the basis for feasibility studies and for describing populations researchers plan to enroll for their grant proposals including: The MSDW enables searches of electronic information that would previously have been prohibitively time-consuming.

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